Yes, prostaglandins can influence the development and progression of cancer. Prostaglandin E2 (PGE2) has been shown to promote tumor growth by stimulating angiogenesis, cell proliferation, and the inhibition of apoptosis. This makes the study of prostaglandins highly relevant in cancer epidemiology. Researchers are particularly interested in how the inhibition of COX-2, and consequently PGE2, might reduce the risk or progression of cancers such as colorectal cancer.
