Are There Any Therapeutic Approaches Targeting CSCs?
Several therapeutic approaches are being explored to target CSCs:
1. Targeting Surface Markers: Drugs and antibodies that target specific surface markers on CSCs are being developed. 2. Inhibiting Signaling Pathways: Pathways such as Wnt, Notch, and Hedgehog, which are crucial for CSC survival and self-renewal, are potential targets for therapy. 3. Inducing Differentiation: Forcing CSCs to differentiate into non-stem-like cells can make them more susceptible to conventional therapies.
