Combination antibiotic therapy is used for several reasons:
Synergistic Effect: Some antibiotics work better together, producing a synergistic effect that enhances their efficacy. Broad-Spectrum Coverage: It provides coverage against a wider range of pathogens, including both Gram-positive and Gram-negative bacteria. Prevention of Resistance: Using multiple antibiotics can prevent the emergence of resistant bacterial strains. Empiric Therapy: It is often used in empirical treatment when the causative pathogen is unknown, ensuring that at least one antibiotic is effective against the infecting organism.
