Cluster RCTs are particularly advantageous in certain contexts within epidemiological research:
Intervention Delivery: When an intervention is easier or more practical to deliver at the group level, such as in schools, communities, or medical practices. Contamination Prevention: To prevent contamination, where individuals in different intervention arms might influence each other if they were randomized individually. Ethical Considerations: In some cases, it may be ethically preferable to randomize clusters rather than individuals, especially in public health interventions.