1. Misinformation: The spread of false or misleading information, especially through social media, can lead to misconceptions about the safety and efficacy of public health measures. 2. Distrust in Authorities: Historical and contemporary instances of unethical practices can erode trust in public health authorities. 3. Cultural Beliefs: Cultural and religious beliefs may conflict with certain public health interventions, such as vaccinations or the use of certain medications. 4. Personal Freedom: Some individuals view public health mandates as infringements on personal freedom and autonomy. 5. Fear of Side Effects: Concerns about potential adverse effects of vaccines or treatments can lead to hesitancy.