Seasonal variations occur due to a combination of factors:
1. Environmental Factors: Changes in temperature, humidity, and precipitation can affect the survival and transmission of pathogens. For instance, influenza peaks in winter months in temperate regions due to lower humidity and temperature. 2. Human Behavior: Seasonal activities such as travel, holidays, and school terms can influence the spread of infectious diseases. Increased indoor activity during colder months can lead to higher transmission of respiratory infections. 3. Biological Factors: The immune system can vary in effectiveness with the seasons, potentially influencing susceptibility to certain infections.