Several strategies can help mitigate the spread of drug resistant strains: 1. Antibiotic Stewardship: Rational use of antibiotics to minimize the development of resistance. 2. Infection Control: Implementing strict hygiene and infection control measures in healthcare settings. 3. Research and Development: Investing in the development of new antibiotics and alternative treatments. 4. Public Education: Educating the public about the responsible use of antibiotics and the dangers of misuse.