What is the epidemiological significance of SERMs?
The epidemiological significance of SERMs lies in their role in the prevention and treatment of diseases with a high incidence and prevalence. For example, breast cancer is one of the most common cancers among women worldwide. Studies have shown that tamoxifen can reduce the incidence of breast cancer in high-risk women by up to 50%. Similarly, raloxifene has been shown to decrease the risk of vertebral fractures in postmenopausal women with osteoporosis.