What is the Epidemiological Evidence for Ethylene Oxide's Carcinogenicity?
Epidemiological studies have provided substantial evidence supporting the carcinogenicity of EO. Case-control and cohort studies have demonstrated a higher incidence of cancers among workers exposed to EO, particularly in industries where it is used extensively. The cohort studies often involve long-term follow-up of workers in EO-producing or using industries, and have shown a significant increase in cancer risk compared to the general population.