Multiple resistance refers to the ability of a microorganism, such as bacteria, viruses, fungi, or parasites, to withstand the effects of multiple antimicrobial drugs. This resistance can occur naturally over time due to genetic mutations or be acquired through horizontal gene transfer. In the context of epidemiology, multiple resistance poses a significant challenge because it complicates the treatment of infections and can lead to longer illness durations, increased healthcare costs, and higher mortality rates.
