Degree centrality is a measure used in network analysis to identify the most connected nodes within a network. In simple terms, it refers to the number of direct connections a particular node has with other nodes. This concept is crucial in epidemiology as it helps identify individuals or entities that potentially play a significant role in the spread of infectious diseases. A node with a high degree centrality is often referred to as a "hub," indicating its importance in maintaining the structure and connectivity of the network.