An aortic aneurysm is a localized enlargement of the aorta, the major blood vessel that supplies blood to the body, caused by a weakening of the artery wall. It can occur in any part of the aorta but is most commonly found in the abdominal segment (abdominal aortic aneurysm, or AAA) and the thoracic segment (thoracic aortic aneurysm, or TAA).