Adrenocorticotropic Hormone (ACTH) is a peptide hormone produced in the anterior pituitary gland. It plays a crucial role in stimulating the production and release of cortisol from the adrenal cortex. Cortisol is instrumental in regulating metabolism, immune response, and stress. The secretion of ACTH is regulated by the hypothalamic corticotropin-releasing hormone (CRH) and is subject to a negative feedback loop involving cortisol levels.
