Socioeconomic Status: Patients with lower income may have difficulty affording medications or accessing healthcare services. Education and Health Literacy: Patients who understand their condition and treatment are more likely to adhere to their medical regimen. Complexity of Treatment: Complex treatments with multiple medications or frequent dosing schedules can reduce adherence. Side Effects: Patients may avoid taking medications that cause unpleasant side effects. Patient-Provider Relationship: Trust and communication between healthcare providers and patients are crucial for adherence.