Despite the best efforts, several challenges can hinder participant engagement:
1. Mistrust: Participants may distrust researchers or institutions, particularly in communities with a history of unethical research practices. 2. Lack of Awareness: Potential participants may not be aware of the study or its importance. 3. Burden of Participation: The time and effort required to participate can be a significant deterrent, especially for individuals with busy schedules or limited resources.
