The risks of polypharmacy are multifaceted and include:
- Adverse Drug Reactions (ADRs): The more medications a person takes, the higher the likelihood of experiencing ADRs, which can range from mild to life-threatening. - Drug-Drug Interactions: Combining multiple drugs can result in interactions that enhance or diminish the effects of one or more of the medications, leading to unintended consequences. - Non-Adherence: Managing several medications can be confusing, leading to poor adherence and suboptimal therapeutic outcomes. - Cognitive Impairment and Falls: Some medications may affect cognitive function or balance, increasing the risk of falls and related injuries, particularly in older adults.
