What are the Methods to Study Cellular Heterogeneity?
Various advanced techniques are employed to study cellular heterogeneity. Single-cell sequencing allows for the analysis of genetic and transcriptomic variations at the single-cell level. Flow cytometry and mass cytometry enable the characterization of phenotypic and functional differences among cell populations. Additionally, imaging techniques such as multiplex immunohistochemistry and in situ hybridization can provide spatial context to cellular heterogeneity within tissues.