What are the Methods for Studying HLA in Populations?
Epidemiologists use various methods to study HLA in populations, including genotyping and serotyping. Genotyping involves sequencing DNA to identify specific HLA alleles, while serotyping uses antibodies to detect HLA proteins on the surface of cells. Advances in molecular biology techniques have made it easier to perform large-scale HLA studies, providing detailed information about HLA diversity and its association with diseases.