While zanamivir is effective, it does have limitations:
1. Timing of Administration: For optimal efficacy, zanamivir must be administered within 48 hours of symptom onset, which requires quick diagnosis and access to the medication. 2. Inhalation Route: The need for inhalation can be a barrier for some patients, particularly young children, elderly individuals, and those with respiratory conditions. 3. Resistance: Although less common than with oseltamivir, there is potential for the influenza virus to develop resistance to zanamivir, which could limit its effectiveness.