Despite its advantages, the RPR test has some limitations:
1. False Positives: Non-specific antibodies can be produced in conditions other than syphilis, leading to false-positive results. These conditions include pregnancy, autoimmune diseases, and certain viral infections. 2. False Negatives: In the early or late stages of syphilis, the antibody levels might be too low to detect, resulting in false-negative results. 3. Non-Specificity: The test does not differentiate between syphilis and other conditions that may cause similar antibody production.
