While MSE is a useful metric, it has some limitations:
Sensitivity to Outliers: Because it squares the errors, MSE can be heavily influenced by outliers, which may not always be desirable. Interpretability: The units of MSE are the square of the units of the original data, which can make interpretation less intuitive. Assumption of Equal Weight: MSE assumes that all errors are of equal importance, which may not always be the case in epidemiological studies.