acth stimulation test

What are the Limitations and Challenges?

One major limitation is that the test may not differentiate between primary and secondary adrenal insufficiency. Additionally, factors like acute illness, [medications](https://), and stress can affect cortisol levels, leading to false positives or negatives. Logistical challenges such as the need for multiple blood draws and specialized equipment can also limit the test's applicability in resource-poor settings.

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