What Are the Epidemiological Implications of Immunosenescence?
From an epidemiological perspective, immunosenescence impacts the incidence, prevalence, and severity of infectious diseases in older adults. For example, influenza and pneumonia are more common and severe in elderly populations. Additionally, vaccine efficacy tends to be lower in older adults due to their impaired immune responses, necessitating tailored vaccination strategies, such as higher-dose vaccines or adjuvanted vaccines.
