1. Cultural Beliefs: Misconceptions or deeply-rooted cultural beliefs can lead to resistance to adopting new health practices or accepting vaccination. 2. Misinformation: The spread of misinformation through social media and other channels can fuel resistance. 3. Institutional Inertia: Established norms and routines within healthcare institutions may resist new protocols. 4. Fear and Anxiety: People may fear new treatments or vaccines due to potential side effects or distrust in the healthcare system. 5. Economic Factors: Financial implications of new interventions can lead to resistance from both individuals and institutions.