Despite its advantages, there are several challenges associated with using LC-MS in epidemiology:
1. Complex Sample Preparation: Preparing biological samples for LC-MS analysis can be time-consuming and requires expertise. 2. Data Interpretation: The data generated by LC-MS is complex and requires sophisticated software and statistical tools for accurate interpretation. 3. Cost: The equipment and maintenance costs for LC-MS are high, which can be a limiting factor for some laboratories.