What Are the Challenges in Using Protein Synthesis Inhibitors?
One of the main challenges is the development of resistance, which can occur through various mechanisms such as mutations in target genes, efflux pumps that expel the inhibitor, or enzymatic degradation of the inhibitor. Additionally, there can be side effects and toxicity associated with the use of protein synthesis inhibitors, which can limit their applicability. The development of new inhibitors that are both effective and safe is an ongoing area of research.
