What Are the Challenges in Tracking Viral Evolution?
One of the main challenges is the high mutation rate of many viruses, which can lead to rapid changes in their genomes. This makes it difficult to keep up with the evolving strains. Additionally, limited access to samples, especially in remote or resource-limited settings, can hinder surveillance efforts. There is also the challenge of differentiating between mutations that have significant impacts on viral properties and those that are neutral.