Several challenges can hinder the effectiveness of TB screening programs:
Resource constraints: Limited funding and healthcare infrastructure can impact the ability to screen and treat patients effectively. Stigma and discrimination: Fear of stigmatization can prevent individuals from seeking screening and treatment. False positives/negatives: No screening method is perfect, and both TST and IGRAs can yield inaccurate results. Compliance: Ensuring that patients complete the full course of treatment for LTBI or active TB is crucial but often challenging.
