What Are the Challenges in Studying Minor Genetic Variations?
One of the main challenges is the complexity of the human genome and the polygenic nature of most diseases. Many diseases are influenced by multiple genetic variations, each contributing a small effect, making it difficult to pinpoint specific genetic factors. Additionally, environmental factors and lifestyle choices also play a significant role in disease development, further complicating the analysis. Another challenge is the need for large sample sizes to achieve statistically significant results, which can be resource-intensive and time-consuming.
