Risk assessment faces several challenges, such as: - Data Quality: Incomplete or low-quality data can lead to inaccurate risk estimates. - Uncertainty and Variability: Differentiating between uncertainty due to lack of knowledge and variability inherent in biological systems can be complex. - Model Limitations: Predictive models may not always capture the complexity of real-world exposures and outcomes. - Ethical Considerations: Balancing risk with economic and social factors can pose ethical dilemmas.