What Are the Challenges in Implementing Adjustments?
Implementing multiple comparison adjustments is not without challenges. Some of these include:
Choosing the Appropriate Method: Different methods have different strengths and weaknesses. Selecting the most suitable one depends on the study design and the nature of the hypotheses being tested. Loss of Power: While adjustments reduce the risk of Type I errors, they can also reduce the statistical power of the study, increasing the risk of Type II errors. Complexity: More sophisticated methods like the FDR require a higher level of statistical expertise, which may not be available in all research settings.
