Implementing appropriate follow-up schedules can present several challenges:
1. Loss to Follow-Up: Participants dropping out of the study can introduce bias and reduce the power of the study. Strategies such as regular contact, incentives, and ensuring participant convenience can mitigate this issue. 2. Timing and Coordination: Coordinating follow-up visits, especially in multi-center studies, requires meticulous planning and resource allocation. 3. Data Management: Collecting and managing longitudinal data over multiple follow-up intervals demands robust data management systems and protocols.
