Several challenges complicate the eradication of polio:
1. Conflict and Insecurity: Areas of conflict pose significant barriers to vaccination efforts and surveillance. 2. Vaccine-Derived Poliovirus (VDPV): In rare cases, the oral polio vaccine can mutate and lead to vaccine-derived poliovirus, which can spread in under-immunized communities. 3. Misinformation: Misinformation and vaccine hesitancy can lead to lower vaccination rates, risking outbreaks. 4. Logistical Issues: Achieving and maintaining high vaccination coverage in remote or densely populated areas can be logistically challenging.
