Despite their advantages, eCRFs also present some challenges, including:
Technical Issues: Implementing and maintaining eCRFs requires technical expertise and resources, which may be a barrier for some research institutions. User Training: Effective use of eCRFs requires training for researchers and data entry personnel, which can be time-consuming and costly. Initial Costs: The initial setup costs for eCRFs can be high, particularly for small-scale studies or organizations with limited budgets. Data Migration: Transitioning from paper-based to electronic systems may involve complex data migration processes and potential data loss or discrepancies.
