What are the Challenges Associated with Combination Adjuvants?
While combination adjuvants offer many benefits, they also present certain challenges:
1. Regulatory Hurdles: The complexity of combination adjuvants can make regulatory approval more challenging, as comprehensive studies are required to demonstrate safety and efficacy.
2. Manufacturing Complexity: Producing combination adjuvants can be more complex and costly compared to single-component adjuvants.
3. Potential for Adverse Effects: The interaction between different adjuvant components may lead to unforeseen adverse effects, necessitating thorough preclinical and clinical testing.
