RNA-Seq offers several advantages over traditional methods such as microarray analysis. It provides a more comprehensive and unbiased view of the transcriptome, allowing for the detection of rare transcripts and novel isoforms. RNA-Seq also has a higher dynamic range, enabling the quantification of transcripts with varying levels of abundance. Additionally, it allows for the identification of single nucleotide polymorphisms (SNPs) and other genetic variations that may influence gene expression.