1. High Throughput: NGS can sequence thousands to millions of DNA or RNA molecules simultaneously, facilitating large-scale epidemiological studies. 2. Speed and Efficiency: Traditional sequencing methods are time-consuming. NGS accelerates the process, providing timely data crucial for public health interventions. 3. Comprehensive Data: NGS provides detailed genetic information, which helps in understanding pathogen evolution and transmission dynamics. 4. Cost-Effective: Over time, the cost per base pair of sequencing has decreased, making it accessible for routine epidemiological surveillance.