Chromosomal disorders are conditions that arise from abnormalities in the number or structure of chromosomes. These disorders can lead to a variety of health and developmental issues. Chromosomes are structures within cells that contain DNA, the genetic material that determines an individual's traits and functions. Humans typically have 46 chromosomes, arranged in 23 pairs. Chromosomal abnormalities can be numerical (such as trisomy or monosomy) or structural (such as deletions, duplications, translocations, and inversions).