The safety of implants is monitored through post-market surveillance and adverse event reporting systems. Agencies like the [FDA](https://www.fda.gov/) and [EMA](https://www.ema.europa.eu/) play a crucial role in this process. Epidemiological studies, including cohort studies and case-control studies, are used to gather data on long-term safety and effectiveness. Registries for specific types of implants, such as joint replacement registries, are also valuable resources.