Constructing a Jacobian matrix involves the following steps:
1. Model Formulation: Develop a system of differential equations representing the disease dynamics. For example, the SIR model consists of equations for Susceptible (S), Infected (I), and Recovered (R) populations.
2. Partial Derivatives: Compute the first-order partial derivatives of each equation with respect to each variable in the system. These derivatives form the elements of the Jacobian matrix.
3. Matrix Assembly: Arrange these partial derivatives into a matrix. For an SIR model, the Jacobian might look like this: