The calculation involves assigning a score to each of the 19 comorbid conditions included in the index. Each condition is given a weight ranging from 1 to 6, based on its associated risk of mortality. The scores are then summed to produce a single composite score for an individual. For example, a patient with diabetes (score 1), myocardial infarction (score 1), and chronic pulmonary disease (score 1) would have a total score of 3.