To generate Level I evidence, researchers design RCTs with specific criteria:
1. Randomization: Participants are randomly assigned to intervention or control groups to eliminate selection bias. 2. Control Group: The presence of a control group helps compare the intervention's effectiveness against no intervention or standard treatment. 3. Blinding: Blinding of participants and researchers to the intervention reduces observer bias. 4. Large Sample Size: A large sample size increases the study's power to detect significant effects.
