Chagas disease is primarily transmitted through contact with the feces of infected triatomine bugs. When the bug feeds on human blood, it often defecates near the bite site. The parasite enters the host's body through mucous membranes, cuts, or scratches. Other modes of transmission include congenital transmission from mother to child, blood transfusions, organ transplants, and consumption of contaminated food or beverages. Each mode of transmission has specific epidemiological implications, particularly in urban and rural settings.