Identification of Benefits and Risks: This involves listing all potential positive and negative outcomes associated with the intervention. Quantification: Where possible, benefits and risks are quantified using data from clinical trials, observational studies, or epidemiological models. Comparison: The quantified benefits and risks are compared using various statistical and analytical methods, such as cost-benefit analysis or quality-adjusted life years (QALYs). Decision-Making: Finally, a decision is made based on the comparison, often involving input from multiple stakeholders, including the public.