How Has TXA Been Studied in Epidemiological Research?
Numerous randomized controlled trials and observational studies have assessed the efficacy and safety of tranexamic acid. The CRASH-2 trial, a large-scale international study, demonstrated a significant reduction in mortality when TXA was administered to trauma patients within three hours of injury. Similarly, the WOMAN trial showed that TXA reduces the risk of death due to bleeding in women with postpartum hemorrhage.