The effectiveness of AMTSL has been demonstrated in numerous epidemiological studies. For instance, a Cochrane review of randomized controlled trials found that AMTSL reduces the risk of PPH by up to 60%. These findings are supported by large-scale observational studies and meta-analyses that show a consistent reduction in blood loss and the need for blood transfusions. The high level of evidence underscores the importance of AMTSL in preventing PPH and improving maternal health outcomes.