The GPEI operates through a multi-faceted strategy: 1. Vaccination Campaigns: Mass immunization drives to ensure all children receive the polio vaccine. 2. Surveillance: Monitoring and detecting polio cases to respond swiftly to outbreaks. 3. Outbreak Response: Rapid intervention in areas where polio is detected to prevent further spread. 4. Community Engagement: Educating communities about the importance of vaccination and encouraging participation.