How Do Researchers Conduct Genetic Epidemiology Studies?
Genetic epidemiology studies typically employ several methodologies:
Family Studies: These studies investigate the inheritance patterns of diseases within families to identify genetic components. Twin Studies: By comparing disease concordance between monozygotic (identical) and dizygotic (fraternal) twins, researchers can estimate the heritability of diseases. Genome-Wide Association Studies (GWAS): GWAS involve scanning the genomes of large populations to identify genetic variants associated with specific diseases. Candidate Gene Studies: These studies focus on specific genes thought to be involved in a disease, based on prior knowledge.