genome wide association studies

How Do GWAS Work?

The process of conducting a GWAS typically involves several key steps. First, researchers gather a large cohort of participants, both affected (cases) and unaffected (controls) by the disease in question. Each participant's DNA is then genotyped, which involves identifying and cataloging SNPs across the genome. Statistical analyses are then performed to find SNPs that show significant associations with the disease. These identified SNPs can point to specific genes or genomic regions that may play a role in the disease's development.

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