How do Genetic Polymorphisms Affect Disease Prevention and Treatment?
Knowledge of genetic polymorphisms can enhance disease prevention and treatment strategies. For example, individuals with certain polymorphisms in the BRCA1 and BRCA2 genes have a higher risk of breast and ovarian cancers and may benefit from more rigorous screening or preventive measures. In treatment, polymorphisms in the TPMT gene can affect how patients metabolize thiopurine drugs, guiding dosage adjustments to avoid adverse effects.
